Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073867 | 1.00 | POLB (0.54) | POLBMEN1KMT2AJAK3RXFP1 | |
| SCHEMBL25073828 | 0.90 | RXFP1 (0.47) | POLBMEN1KMT2ARXFP1LMNA | |
| SCHEMBL30279189 | 0.85 | DDR1 (0.44) | POLBMEN1KMT2AROCK1ROCK2 | |
| SCHEMBL25073840 | 0.85 | DDR1 (0.44) | POLBMEN1KMT2AROCK1ROCK2 | |
| SCHEMBL25073769 | 0.84 | KDR (0.45) | POLBKMT2AJAK3RXFP1LMNA | |
| SCHEMBL31746908 | 0.84 | KDR (0.45) | POLBKMT2AJAK3RXFP1LMNA | |
| SCHEMBL31746947 | 0.83 | RXFP1 (0.47) | POLBRXFP1LMNARECQLMAPT | |
| SCHEMBL25073887 | 0.83 | RXFP1 (0.47) | POLBRXFP1LMNARECQLMAPT | |
| SCHEMBL31746936 | 0.82 | TAS2R14 (0.40) | POLBMEN1KMT2ARXFP1LMNA | |
| SCHEMBL25073832 | 0.82 | TAS2R14 (0.40) | POLBMEN1KMT2ARXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |