SCHEMBL31746947

SCHEMBL31746947

Cn1ncc2cc(Nc3cccc4ccn(CC(=O)Nc5cccc(C(F)(F)F)c5)c(=O)c34)ccc21

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.47
MAPT P10636 6/20 0.43
LMNA P02545 4/20 0.43
RECQL P46063 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42
NOTUM Q6P988 1/20 0.42
FSCN1 Q16658 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RORC P51449 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073887 1.00 RXFP1 (0.47) RXFP1MAPTLMNARECQLSMN1; SMN2
SCHEMBL25073757 0.94 TRPA1 (0.47) RXFP1MAPTLMNAPOLBTP53
SCHEMBL31746896 0.94 TRPA1 (0.47) RXFP1MAPTLMNAPOLBTP53
SCHEMBL25073883 0.93 NOTUM (0.41) RXFP1MAPTLMNARECQLSMN1; SMN2
SCHEMBL25073752 0.92 RXFP1 (0.39) RXFP1MAPTLMNASMN1; SMN2HTT
SCHEMBL31746891 0.92 RXFP1 (0.39) RXFP1MAPTLMNASMN1; SMN2HTT
SCHEMBL25073877 0.92 NOTUM (0.42) RXFP1MAPTLMNASMN1; SMN2HTT
SCHEMBL30279170 0.92 NOTUM (0.42) RXFP1MAPTLMNASMN1; SMN2HTT
SCHEMBL31746897 0.90 ALDH1A1 (0.46) MAPTLMNAPOLBTP53NOTUM
SCHEMBL25073760 0.90 ALDH1A1 (0.46) MAPTLMNAPOLBTP53NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed