SCHEMBL31746970

SCHEMBL31746970

Cn1ncc2cc(Nc3cccc4ccn(CC(=O)O)c(=O)c34)cnc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.36
MALT1 Q9UDY8 1/20 0.35
MAPK8 P45983 2/20 0.35
MAPK10 P53779 2/20 0.35
MAPK14 Q16539 2/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK9 P45984 1/20 0.35
KMT2A Q03164 2/20 0.34
RPS6KA2 Q15349 1/20 0.34
ALDH1A1 P00352 2/20 0.34
EGFR P00533 2/20 0.34
POLB P06746 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34
BPTF Q12830 2/20 0.33
BRD4 O60885 2/20 0.33
KAT2B Q92831 2/20 0.33
BRD9 Q9H8M2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073904 1.00 NAMPT (0.36) NAMPTMALT1MAPK8MAPK10MAPK14
SCHEMBL25073908 0.86 NPC1 (0.42) NAMPTMAPK8MAPK10KMT2AALDH1A1
SCHEMBL30279196 0.86 NPC1 (0.42) NAMPTMAPK8MAPK10KMT2AALDH1A1
SCHEMBL25073893 0.86 MALT1 (0.37) MALT1KMT2APOLBFGFR3
SCHEMBL31746921 0.86 MALT1 (0.37) MALT1KMT2APOLBFGFR3
SCHEMBL31162540 0.85 RXFP1 (0.47) ALDH1A1POLBNLRP3
SCHEMBL25073879 0.84 NLRP3 (0.37) MALT1KMT2AALDH1A1POLBNOTUM
SCHEMBL31746919 0.84 NLRP3 (0.37) MALT1KMT2AALDH1A1POLBNOTUM
SCHEMBL25073805 0.83 RXFP1 (0.40) ALDH1A1POLBNOTUMNLRP3
SCHEMBL31746966 0.83 RXFP1 (0.40) ALDH1A1POLBNOTUMNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed