SCHEMBL31747272

SCHEMBL31747272

C#CCOc1ccc(C(=O)OC)cn1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ GABRA5 P31644 11/20 0.46
▸ MAPT P10636 3/20 0.46
▸ NNMT P40261 1/20 0.44
▸ LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31752289 0.84 MAPK1 (0.49) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL4763660 0.83 MAPT (0.63) L3MBTL1GABRA5MAPTNNMT
SCHEMBL31747383 0.81 NNMT (0.58) MAPK1KDM4EL3MBTL1MAPTNNMT
SCHEMBL21394819 0.81 MAPT (0.70) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL23537708 0.80 MAPK1 (0.57) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL31215048 0.80 MAPK1 (0.57) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL65277 0.79 NNMT (0.68) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL23537880 0.78 MAPK1 (0.56) MAPK1KDM4EL3MBTL1GABRA5MAPT
SCHEMBL254800 0.78 MAPT (0.66) L3MBTL1MAPTLMNA
SCHEMBL23538185 0.77 MAPK1 (0.54) MAPK1KDM4EL3MBTL1GABRA5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
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