Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 9/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | IL1B | P01584 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135733 | 0.94 | CRBN (0.58) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL27099085 | 0.94 | CRBN (0.58) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL31752706 | 0.93 | CRBN (0.53) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL31129754 | 0.93 | CRBN (0.52) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL31753300 | 0.91 | CRBN (0.54) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL23250121 | 0.89 | CRBN (0.50) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL29874231 | 0.89 | CRBN (0.50) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL30936821 | 0.88 | CRBN (0.52) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL31129437 | 0.88 | IKZF1 (0.49) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL25034694 | 0.88 | CRBN (0.53) | CRBNIKZF3DDB1IKZF1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |