SCHEMBL3174757

SCHEMBL3174757

CN(C)S(=O)(=O)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.57
HSD17B10 Q99714 2/20 0.56
USP2 O75604 1/20 0.56
HPGD P15428 1/20 0.56
CA2 P00918 3/20 0.52
CA1 P00915 2/20 0.52
PRSS1 P07477 2/20 0.52
PRSS2 P07478 2/20 0.52
PRSS3 P35030 2/20 0.52
FAAH O00519 1/20 0.52
ELANE P08246 1/20 0.52
PRTN3 P24158 1/20 0.52
CA5A P35218 1/20 0.52
CA9 Q16790 1/20 0.52
CNR2 P34972 1/20 0.49
TSHR P16473 2/20 0.48
NPY5R Q15761 1/20 0.48
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7593278 0.83 PRSS1 (0.54) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL14951927 0.83 HSP90AA1 (0.53) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL11707925 0.81 HSP90AA1 (0.52) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL6822183 0.81 HSP90AA1 (0.52) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL3822620 0.81 HSP90AA1 (0.61) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL8294096 0.81 CNR2 (0.53) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL4569291 0.81 HSP90AA1 (0.52) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL10286193 0.80 KMT2A (0.46) HSD17B10USP2HPGDCA2CA1
SCHEMBL4491486 0.80 HPGD (0.53) HSP90AA1HSD17B10USP2HPGDCA2
SCHEMBL3192672 0.80 CNR2 (0.65) HSP90AA1HSD17B10USP2HPGDCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109251588-B Inorganic nano material ink, preparation method and application thereof, and QLED device TCL科技集团股份有限公司 2021-06-22 CN claimed
US-20230321050-A1 Heterocyclic Compounds and Uses Thereof MILLENNIUM PHARMACEUTICALS, INC. 2023-10-12 US disclosed
US-11547697-B2 Heterocyclic compounds and uses thereof MILLENNIUM PHARMACEUTICALS, INC. (US) 2023-01-10 US disclosed
CN-109251588-B Inorganic nano material ink, preparation method and application thereof, and QLED device TCL科技集团股份有限公司 2021-06-22 CN disclosed
US-20200131335-A1 SURFACE ACTIVE ADJUVANT RHODIA OPERATIONS (FR) 2020-04-30 US disclosed
EP-3612604-A1 SURFACE ACTIVE ADJUVANT Rhodia Operations (FR) 2020-02-26 EP disclosed
WO-2020035124-A1 SURFACE ACTIVE ADJUVANT FOR COATINGS RHODIA OPERATIONS (FR) 2020-02-20 WO disclosed
US-20190350906-A1 Heterocyclic Compounds and Uses Thereof INTELLIKINE, LLC 2019-11-21 US disclosed
US-10472352-B2 Rac inhibitors Geneyus LLC (US) 2019-11-12 US disclosed
US-10329263-B2 Disubstituted 1, 2, 4-triazine compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2019-06-25 US disclosed
WO-1995009158-A1 TRICYCLIC DERIVATIVES ZENECA LIMITED (GB) 1995-04-06 WO disclosed
US-5328884-A Salicylic acid salt,and amide or sulfonamide as developer KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-07-12 US disclosed
WO-1994007869-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1994-04-14 WO disclosed
US-5250108-A Mixture of salicylic acid salt, amide and sulfonamide compounds KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1993-10-05 US disclosed
EP-0548813-A1 Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines Bristol-Myers Squibb Company (US) 1993-06-30 EP disclosed
EP-0099329-B1 DITHIO COMPOUNDS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE Zyma SA (CH) 1990-10-31 EP disclosed
US-4946861-A TREATMENT OF LIVER DISORDERS ZYMA SA (CH) 1990-08-07 US disclosed
US-4818765-A TREATING LIVER, RESPIRATORY TRACT, VASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1989-04-04 US disclosed
EP-0099329-A1 Dithio compounds, pharmaceutical preparations containing them and their use Zyma SA (CH) 1984-01-25 EP disclosed
US-3933869-A Preparation of organic radiohalogen compounds SCHERING AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321050-A1 Heterocyclic Compounds and Uses Thereof PIK3CA, PIK3CD, PIK3CB HSP90AA1 1309/4885HSD17B10 1819/4885USP2 2882/4885
US-10329263-B2 Disubstituted 1, 2, 4-triazine compound NR3C2, REN, NR5A1 HSP90AA1 2529/4885HSD17B10 120/4885USP2 2478/4885
US-11547697-B2 Heterocyclic compounds and uses thereof PIK3CA, PIK3CD, PIK3CB HSP90AA1 1309/4885HSD17B10 1819/4885USP2 2882/4885
US-10472352-B2 Rac inhibitors ARHGDIB, ARHGDIA, RAC1 HSP90AA1 1039/4885HSD17B10 3190/4885USP2 3349/4885
US-20190350906-A1 Heterocyclic Compounds and Uses Thereof PIK3CA, PIK3CD, PIK3CB HSP90AA1 1309/4885HSD17B10 1819/4885USP2 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.