⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748684 | 0.85 | — | — | |
| SCHEMBL31748315 | 0.85 | JAK2 (0.31) | — | |
| SCHEMBL31748579 | 0.83 | SYK (0.30) | — | |
| SCHEMBL31748640 | 0.82 | DGAT1 (0.33) | — | |
| SCHEMBL31748473 | 0.81 | — | — | |
| SCHEMBL31748697 | 0.74 | GABRA5 (0.34) | — | |
| SCHEMBL31748621 | 0.70 | SYK (0.30) | — | |
| SCHEMBL31748668 | 0.69 | DGAT1 (0.33) | — | |
| SCHEMBL31748374 | 0.68 | EGFR (0.31) | — | |
| SCHEMBL31748550 | 0.66 | DGAT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | BIOLEXIS THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |