SCHEMBL31748612

SCHEMBL31748612

O=C(Nc1ccc2nc(-c3ccccc3F)[nH]c2c1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ NR2E3 Q9Y5X4 2/20 0.60
▸ MMP2 P08253 4/20 0.59
▸ MMP9 P14780 4/20 0.59
▸ MMP8 P22894 4/20 0.59
▸ MMP13 P45452 4/20 0.59
▸ CYP2C9 P11712 1/20 0.58
▸ CYP2C19 P33261 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ COMT P21964 1/20 0.57
▸ HDAC6 Q9UBN7 1/20 0.55
▸ KDR P35968 2/20 0.54
▸ CHEK2 O96017 1/20 0.54
▸ MET P08581 1/20 0.53
▸ ADORA2A P29274 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26597183 1.00 MAPT (0.63) MAPTMAPK1NR2E3MMP2MMP9
SCHEMBL30667671 0.84 MMP2 (0.76) MAPTMAPK1NR2E3MMP2MMP9
SCHEMBL26597177 0.84 MMP2 (0.76) MAPTMAPK1NR2E3MMP2MMP9
SCHEMBL26597194 0.84 MMP2 (0.72) MAPTMAPK1NR2E3MMP2MMP9
SCHEMBL31748482 0.84 MMP2 (0.72) MAPTMAPK1NR2E3MMP2MMP9
Hydrochloric Acid SCHEMBL19149753 0.83 MMP2 (0.74) MAPTMAPK1NR2E3MMP2MMP9
SCHEMBL1251033 0.83 HDAC6 (0.58) MAPTNR2E3CYP2C9CYP2C19KMT2A
SCHEMBL26597190 0.82 NR2E3 (0.57) MAPTNR2E3CYP2C9CYP2C19KMT2A
SCHEMBL31748782 0.82 NR2E3 (0.57) MAPTNR2E3CYP2C9CYP2C19KMT2A
SCHEMBL31748726 0.82 MMP2 (0.70) MAPTMAPK1NR2E3MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, CCR10, IL2 MAPT 4593/4885MAPK1 1275/4885NR2E3 2814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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