Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12061613 | 0.81 | ERN1 (0.31) | ERN1 | |
| SCHEMBL5514290 | 0.81 | HSD17B10 (0.34) | KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL12051125 | 0.79 | HCAR3 (0.42) | ERN1KDM4EALDH1A1TDP1 | |
| SCHEMBL248719 | 0.78 | ERN1 (0.50) | ERN1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL9849607 | 0.76 | MEN1 (0.32) | TSHR | |
| SCHEMBL30607215 | 0.76 | MEN1 (0.32) | TSHR | |
| SCHEMBL29012715 | 0.74 | ERN1 (0.37) | ERN1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL150019 | 0.73 | ERN1 (0.46) | ERN1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL5514321 | 0.73 | APP (0.31) | — | |
| SCHEMBL21639542 | 0.72 | ERN1 (0.40) | ERN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114896-B1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INST (AU) | 2015-07-22 | — | — | EP | disclosed |
| EP-2114896-B1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INST (AU) | 2015-07-22 | — | — | EP | disclosed |
| US-9023998-B2 | Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing | CARNEGIE MELLON UNIVERSITY (US) | 2015-05-05 | — | — | US | disclosed |
| US-9023998-B2 | Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing | CARNEGIE MELLON UNIVERSITY (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | CARNEGIE MELLON UNIVERSITY | 2014-08-28 | — | — | US | disclosed |
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | CARNEGIE MELLON UNIVERSITY | 2014-08-28 | — | — | US | disclosed |
| US-8796277-B2 | Radioprotector compounds and related methods | PETER MACCALLUM CANCER INSTITUTE (AU) | 2014-08-05 | — | — | US | disclosed |
| US-8796277-B2 | Radioprotector compounds and related methods | PETER MACCALLUM CANCER INSTITUTE (AU) | 2014-08-05 | — | — | US | disclosed |
| US-20100022557-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INSTITUTE (AU) | 2010-01-28 | — | — | US | disclosed |
| US-20100022557-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INSTITUTE (AU) | 2010-01-28 | — | — | US | disclosed |
| EP-2114896-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | Peter MacCallum Cancer Institute (AU) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008074091-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INSTITUTE (AU) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | FUCA1, TYR, HBG2 | ERN1 3278/4885KDM4E 3374/4885ALDH1A1 1815/4885 |
| US-20100022557-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | RAD50, ERCC2, XRCC6 | ERN1 1419/4885KDM4E 2584/4885ALDH1A1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.