Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750399 | 0.87 | KDM4E (0.44) | KDM4EL3MBTL1TDP1MAPTMEN1 | |
| SCHEMBL31750096 | 0.78 | SMN1; SMN2 (0.43) | KDM4EL3MBTL1TDP1MAPTMEN1 | |
| SCHEMBL23841768 | 0.78 | USP7 (0.34) | KDM4ESMN1; SMN2MAPK1HPGDHTT | |
| SCHEMBL31750249 | 0.74 | NOTUM (0.34) | TP53 | |
| SCHEMBL21123278 | 0.74 | KMT2A (0.34) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31750938 | 0.73 | L3MBTL1 (0.40) | KDM4EL3MBTL1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL31751049 | 0.73 | KDM4E (0.43) | KDM4EL3MBTL1TDP1MAPTMEN1 | |
| SCHEMBL18070735 | 0.72 | KMT2A (0.33) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31751055 | 0.71 | KDM4E (0.42) | KDM4EL3MBTL1TDP1MAPTMEN1 | |
| SCHEMBL24440124 | 0.71 | GAA (0.43) | KDM4EL3MBTL1TDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |