Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750399 | 0.84 | KDM4E (0.44) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31751049 | 0.83 | KDM4E (0.43) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31750118 | 0.74 | KDM4E (0.40) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31750482 | 0.73 | RXRA (0.42) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31750045 | 0.71 | KDM4E (0.42) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL1028535 | 0.70 | KDM4E (0.43) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31750324 | 0.69 | KDM4E (0.42) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL31750243 | 0.68 | KDM4E (0.42) | KDM4EL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL1429298 | 0.68 | AKR1B1 (0.55) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31750476 | 0.68 | HTR2A (0.43) | HTR2AHTR2CKMOMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |