Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31750107

O=C(O)C(F)(F)F.O=C1NCc2ccccc21

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.70
CA9 Q16790 1/20 0.70
CLK4 Q9HAZ1 3/20 0.49
DYRK1B Q9Y463 3/20 0.49
TYRO3 Q06418 1/20 0.49
NTRK2 Q16620 1/20 0.49
PARP1 P09874 3/20 0.47
PDPK1 O15530 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PARP11 Q9NR21 1/20 0.47
GRM5 P41594 4/20 0.45
AURKA O14965 3/20 0.41
KDR P35968 4/20 0.40
MAP3K9 P80192 1/20 0.40
MAP3K11 Q16584 1/20 0.40
TDP2 O95551 1/20 0.40
CASP3 P42574 1/20 0.40
CASP7 P55210 1/20 0.40
CASP9 P55211 1/20 0.40
CASP6 P55212 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28324274 1.00 CA12 (0.70) CA12CA9CLK4DYRK1BTYRO3
Bicarbonate SCHEMBL21081705 0.88 CA12 (0.84) CA12CA9CLK4DYRK1BTYRO3
Bicarbonate SCHEMBL29928922 0.88 CA12 (0.84) CA12CA9CLK4DYRK1BTYRO3
Trifluoroacetic Acid SCHEMBL28415123 0.84 PARP10 (0.72) CA12CA9PARP1PDPK1PARP10
SCHEMBL4818277 0.84 CA12 (1.00) CA12CA9CLK4DYRK1BTYRO3
SCHEMBL29355184 0.84 CA12 (1.00) CA12CA9CLK4DYRK1BTYRO3
SCHEMBL14896 0.84 CA12 (1.00) CA12CA9CLK4DYRK1BTYRO3
SCHEMBL29002605 0.82 CA12 (0.88) CA12CA9CLK4DYRK1BTYRO3
Hydrochloric Acid SCHEMBL5046932 0.82 CA12 (0.95) CA12CA9CLK4DYRK1BTYRO3
Water SCHEMBL19462703 0.82 CA12 (0.95) CA12CA9CLK4DYRK1BTYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262433-A1 N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS MISSION THERAPEUTICS LIMITED (GB) 2025-12-26 WO disclosed