Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750165 | 0.88 | RXRA (0.37) | RXRARXRBRXRGDGAT2CCNA2 | |
| SCHEMBL31751081 | 0.87 | RXRA (0.36) | RXRARXRBRXRGDGAT2CCNA2 | |
| SCHEMBL31750477 | 0.81 | KDM4E (0.36) | RXRARXRBRXRGDGAT2GAA | |
| SCHEMBL31750777 | 0.68 | RXRA (0.36) | RXRARXRBRXRGDGAT2GAA | |
| SCHEMBL31750490 | 0.67 | RXRA (0.35) | RXRARXRBRXRGDGAT2GAA | |
| SCHEMBL31751088 | 0.66 | RXRA (0.35) | RXRARXRBRXRGDGAT2 | |
| SCHEMBL29959666 | 0.64 | ELANE (0.43) | DGAT2GAA | |
| SCHEMBL19204829 | 0.64 | ELANE (0.43) | DGAT2GAA | |
| SCHEMBL659294 | 0.63 | ATR (0.38) | RXRARXRBRXRGGAA | |
| SCHEMBL25473050 | 0.63 | ATR (0.36) | RXRARXRBRXRGDGAT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |