Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750777 | 0.90 | RXRA (0.36) | RXRARXRBRXRGDGAT2P2RY12 | |
| SCHEMBL31750490 | 0.88 | RXRA (0.35) | RXRARXRBRXRGDGAT2P2RY12 | |
| SCHEMBL31750477 | 0.85 | KDM4E (0.36) | RXRARXRBRXRGDGAT2P2RY12 | |
| SCHEMBL31750140 | 0.81 | DGAT2 (0.34) | RXRARXRBRXRGDGAT2KDM4E | |
| SCHEMBL31750142 | 0.80 | RXRA (0.44) | RXRARXRBRXRGDGAT2P2RY12 | |
| SCHEMBL31751095 | 0.79 | HTR2C (0.34) | DGAT2CNR1RET | |
| SCHEMBL31750483 | 0.77 | RXRA (0.33) | RXRARXRBRXRGDGAT2P2RY12 | |
| SCHEMBL31750482 | 0.76 | RXRA (0.42) | RXRARXRBRXRGP2RY12KDM4E | |
| SCHEMBL24495531 | 0.74 | PPOX (0.38) | RXRARXRBRXRGRETP2RY12 | |
| SCHEMBL28962275 | 0.73 | RXRA (0.37) | RXRARXRBRXRGDGAT2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262250-A1 | GUANFACINE DERIVATIVES AND THEIR USES | NEGIO THERAPEUTICS (BE) | 2025-12-26 | — | — | WO | disclosed |