Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739258 | 0.78 | HDAC2 (0.64) | BTKHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5365142 | 0.73 | KDM4E (0.65) | PDCD1CD274TP53NPC1RAB9A | |
| SCHEMBL786246 | 0.73 | PDCD1 (0.81) | PDCD1CD274HDAC1HDAC2HDAC3 | |
| SCHEMBL17212388 | 0.72 | PDCD1 (0.50) | PDCD1CD274TP53NPC1RAB9A | |
| SCHEMBL31751986 | 0.72 | BTK (0.36) | BTKHDAC1HDAC2HDAC3TP53 | |
| SCHEMBL2606255 | 0.71 | NPC1 (0.64) | PDCD1CD274HDAC1HDAC2HDAC3 | |
| SCHEMBL11284668 | 0.71 | PDCD1 (0.64) | PDCD1CD274NPC1RAB9AKDM4E | |
| SCHEMBL7848398 | 0.71 | KDM4E (0.60) | PDCD1CD274TP53KDM4EALDH1A1 | |
| SCHEMBL6720875 | 0.70 | MEN1 (0.73) | PDCD1CD274NPC1RAB9AKDM4E | |
| SCHEMBL6692379 | 0.70 | HDAC2 (0.58) | HDAC1HDAC2HDAC3TP53HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081045-A9 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-12-26 | — | — | WO | disclosed |