Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753507 | 0.76 | JAK3 (0.38) | BTK | |
| SCHEMBL31753091 | 0.74 | TNIK (0.32) | — | |
| SCHEMBL31753158 | 0.74 | KDM4E (0.42) | SIRT1 | |
| SCHEMBL31751997 | 0.72 | PDCD1 (0.51) | BTKHDAC2HDAC1HDAC3HDAC4 | |
| SCHEMBL29354764 | 0.65 | KDM4E (0.40) | SIRT2SIRT1SIRT3 | |
| SCHEMBL25439186 | 0.62 | KDM4E (0.35) | BTK | |
| SCHEMBL6692379 | 0.59 | HDAC2 (0.58) | HDAC2HDAC1HDAC3HDAC4HDAC8 | |
| SCHEMBL4762075 | 0.58 | ALDH1A1 (0.39) | TP53 | |
| SCHEMBL405604 | 0.58 | — | — | |
| SCHEMBL13739258 | 0.58 | HDAC2 (0.64) | BTKHDAC2HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081045-A9 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-12-26 | — | — | WO | disclosed |