Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753382 | 0.87 | MAPT (0.58) | MAPTGABRA1L3MBTL1 | |
| SCHEMBL31747383 | 0.83 | NNMT (0.58) | NNMTSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL31752289 | 0.83 | MAPK1 (0.49) | NNMTMAPTL3MBTL1 | |
| SCHEMBL23834721 | 0.80 | NNMT (0.62) | NNMTSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL29683986 | 0.80 | NNMT (0.62) | NNMTSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL11551255 | 0.80 | NNMT (0.62) | NNMTSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL1680864 | 0.79 | NNMT (0.61) | NNMTSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL31747364 | 0.78 | PARP10 (0.60) | L3MBTL1 | |
| SCHEMBL6953681 | 0.78 | NNMT (0.59) | NNMTOPRM1OPRD1OPRK1MKNK1 | |
| SCHEMBL31747260 | 0.78 | NNMT (0.45) | NNMTSMN1; SMN2MKNK1MKNK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |