Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31747380 | 0.95 | NNMT (0.44) | NNMTSMN1; SMN2GRM5KDM4EL3MBTL1 | |
| SCHEMBL31747413 | 0.86 | P4HA1 (0.44) | SMN1; SMN2L3MBTL1GABRA5CYP1A2CYP2C19 | |
| SCHEMBL30826948 | 0.84 | NNMT (0.53) | NNMTSMN1; SMN2GRM5KDM4EL3MBTL1 | |
| SCHEMBL31747395 | 0.82 | P4HA1 (0.43) | SMN1; SMN2L3MBTL1GABRA5CYP1A2CYP2C19 | |
| SCHEMBL31747492 | 0.81 | MAPK1 (0.49) | KDM4EL3MBTL1 | |
| SCHEMBL31752610 | 0.78 | NNMT (0.54) | NNMTSMN1; SMN2GRM5L3MBTL1MKNK1 | |
| SCHEMBL31747479 | 0.77 | MAPK1 (0.48) | SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL20463188 | 0.76 | NNMT (0.45) | NNMTSMN1; SMN2GRM5KDM4EL3MBTL1 | |
| SCHEMBL31747312 | 0.76 | MAOB (0.49) | L3MBTL1PARP10CYP2C19 | |
| SCHEMBL29537517 | 0.76 | NNMT (0.52) | NNMTSMN1; SMN2GRM5KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |