Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234462 | 0.87 | ALDH1A1 (0.55) | RAF1MAPK14ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL667897 | 0.84 | RAF1 (1.00) | RAF1MAPK14MAPK13ALDH1A1RIPK2 | |
| SCHEMBL102637 | 0.82 | RAF1 (0.72) | RAF1MAPK14MAPK13RIPK2FLT3 | |
| SCHEMBL4441367 | 0.79 | RAF1 (0.73) | RAF1MAPK14MAPK13ALDH1A1RIPK2 | |
| SCHEMBL15574733 | 0.78 | HDAC1 (0.63) | RAF1MAPK14ALDH1A1RIPK2NAMPT | |
| SCHEMBL938751 | 0.77 | RAF1 (0.80) | RAF1MAPK14MAPK13RIPK2FLT3 | |
| SCHEMBL667449 | 0.77 | RAF1 (0.80) | RAF1MAPK14MAPK13RIPK2FLT3 | |
| SCHEMBL15574578 | 0.77 | NAMPT (0.62) | RAF1NAMPTHTT | |
| SCHEMBL667885 | 0.76 | RAF1 (0.72) | RAF1MAPK14MAPK13ALDH1A1FLT3 | |
| SCHEMBL16990619 | 0.75 | HTT (0.64) | NAMPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-1970375-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2008-09-17 | — | — | EP | disclosed |
| EP-1970375-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | UROD, UTS2R, SLC14A1 | RAF1 2980/4885MAPK14 500/4885MAPK13 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.