Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377843 | 0.87 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL930355 | 0.83 | KMT2A (0.58) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL31751437 | 0.82 | KMT2A (0.54) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL1698808 | 0.82 | KMT2A (0.54) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL31752551 | 0.81 | POLB (0.53) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL29575442 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL14905034 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL378947 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL2932303 | 0.79 | KMT2A (0.51) | KMT2AMEN1ALDH1A1PKMCA12 | |
| SCHEMBL4495296 | 0.78 | AKR1B1 (0.48) | MAPTNPSR1KDM4EAKR1B1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025260159-A1 | ISOINDOLINE AND INDOLINE DERIVATIVE COMPOUNDS, COMBINATIONS, PHARMACEUTICAL COMPOSITIONS, MEDICAMENTS, USE OF THE COMPOUNDS AND METHOD OF TREATMENT OF PAIN | MICROBIOLÓGICA QUÍMICA E FARMACÊUTICA LTDA. (BR) | 2025-12-26 | — | — | WO | disclosed |