Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 4/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801902 | 0.86 | GPR119 (0.53) | GPR119HRH3MGLLABHD6 | |
| SCHEMBL31752871 | 0.85 | GPR119 (0.63) | GPR119 | |
| SCHEMBL31752756 | 0.83 | GPR119 (0.51) | GPR119HRH3JAK2JAK1MGLL | |
| SCHEMBL30801988 | 0.80 | GPR119 (0.48) | GPR119HRH3MGLLABHD6HDAC1 | |
| SCHEMBL31574756 | 0.79 | GPR119 (0.48) | GPR119HRH3MGLLABHD6 | |
| SCHEMBL31752490 | 0.79 | GPR119 (0.48) | GPR119JAK2JAK1HDAC1HDAC2 | |
| SCHEMBL6114639 | 0.79 | GPR119 (0.51) | GPR119MGLL | |
| SCHEMBL31216657 | 0.79 | GPR119 (0.51) | GPR119MGLL | |
| SCHEMBL31574782 | 0.78 | GPR119 (0.45) | GPR119HRH3MGLLABHD6 | |
| SCHEMBL27152201 | 0.78 | ABHD6 (0.51) | GPR119HRH3MGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |