Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15376733 | 0.88 | USP30 (0.54) | CHEK2GPR119SENP8SENP6USP30 | |
| SCHEMBL6182215 | 0.87 | USP30 (0.53) | CHEK2GPR119USP30 | |
| SCHEMBL24117869 | 0.87 | USP30 (0.47) | CHEK2GPR119PARP10SENP8SENP6 | |
| SCHEMBL21825204 | 0.87 | CHEK2 (0.48) | CHEK2GPR119PARP10USP30PDE4B | |
| SCHEMBL21887531 | 0.87 | CHEK2 (0.48) | CHEK2GPR119PARP10USP30PDE4B | |
| SCHEMBL5530954 | 0.87 | CHEK2 (0.67) | CHEK2GPR119PARP10PDE4B | |
| SCHEMBL23830846 | 0.85 | OPRK1 (0.55) | CHEK2USP30OPRK1KCNH2 | |
| SCHEMBL28670992 | 0.85 | USP30 (0.53) | CHEK2GPR119USP30 | |
| SCHEMBL12788093 | 0.85 | USP30 (0.53) | CHEK2GPR119USP30 | |
| SCHEMBL3343250 | 0.83 | USP30 (0.52) | CHEK2GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |