SCHEMBL31753656

SCHEMBL31753656

NC(=S)NN=Cc1ccc(N)cn1

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RRM2 P31350 9/20 0.67
KDM4E B2RXH2 1/20 0.51
RRM1 P23921 1/20 0.50
RRM2B Q7LG56 1/20 0.50
CISD1 Q9NZ45 1/20 0.50
CTH P32929 1/20 0.47
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749775 1.00 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL4382591 1.00 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL783293 0.84 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL29420113 0.84 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL30094126 0.84 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL783292 0.84 RRM2 (0.67) RRM2KDM4ERRM1RRM2BCISD1
SCHEMBL8685653 0.77 MAPT (0.64) RRM2KDM4E
SCHEMBL6261110 0.76 RRM2 (0.71) RRM2KDM4ECTHNCOA1NCOA3
SCHEMBL6261112 0.76 RRM2 (0.71) RRM2KDM4ECTHNCOA1NCOA3
SCHEMBL534248 0.75 TOP2A (0.68) RRM2RRM1RRM2BCISD1CTH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025260130-A1 COMPOUNDS AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2025-12-26 WO disclosed