Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3165912 | 0.84 | SCN5A (0.44) | SCN5ASCN9ASCN10A | |
| SCHEMBL9754189 | 0.80 | SCN5A (0.47) | SCN5ASCN9ASCN10A | |
| SCHEMBL3166761 | 0.78 | — | — | |
| SCHEMBL4126064 | 0.78 | SCN5A (0.46) | SCN5ASCN9ASCN10A | |
| SCHEMBL3165979 | 0.78 | SCN5A (0.37) | SCN5ASCN9ASCN10A | |
| SCHEMBL3167552 | 0.78 | SCN5A (0.37) | SCN5ASCN9ASCN10A | |
| SCHEMBL3161034 | 0.77 | LTA4H (0.35) | — | |
| SCHEMBL16330807 | 0.76 | SCN5A (0.52) | SCN5ASCN9ASCN10A | |
| SCHEMBL3167305 | 0.76 | L3MBTL1 (0.43) | — | |
| SCHEMBL3166633 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645792-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090005352-A1 | Prodrugs of Propofol, Compositions and Uses Thereof | XENOPORT, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-7241807-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | CYP2C19, CYP3A5, CYP3A4 | SCN5A 151/4885SCN9A 440/4885SCN10A 563/4885 |
| US-20090005352-A1 | Prodrugs of Propofol, Compositions and Uses Thereof | CYP2C19, CYP3A5, CYP3A4 | SCN5A 151/4885SCN9A 440/4885SCN10A 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.