Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 10/20 | 0.66 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.66 |
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | NPY2R | P49146 | 1/20 | 0.65 |
| ▸ | NPY4R | P50391 | 1/20 | 0.65 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376999 | 0.88 | F2RL1 (0.58) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| SCHEMBL29671012 | 0.87 | NTSR1 (0.54) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| Laminin SCHEMBL29354054 | 0.87 | NTSR1 (0.56) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| Laminin SCHEMBL29359946 | 0.87 | NTSR1 (0.56) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| SCHEMBL30536835 | 0.87 | NPY4R (0.80) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| SCHEMBL29474946 | 0.86 | NPY1R (0.61) | NTSR1NTSR2NPY1RNPY2RNPY4R | |
| Dynorphin SCHEMBL31009050 | 0.85 | OPRD1 (0.67) | NPY1RNPY2RNPY4ROPRK1OPRD1 | |
| Dynorphin SCHEMBL30415373 | 0.85 | OPRD1 (0.67) | NPY1RNPY2RNPY4ROPRK1OPRD1 | |
| Dynorphin SCHEMBL30914084 | 0.85 | OPRD1 (0.67) | NPY1RNPY2RNPY4ROPRK1OPRD1 | |
| Dynorphin SCHEMBL29598868 | 0.85 | OPRD1 (0.67) | NPY1RNPY2RNPY4ROPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121243345-A | EGFR-TKI drug resistance inhibitor and application thereof | 北京大学第一医院(北京大学第一临床医学院) | 2026-01-02 | — | — | CN | disclosed |