Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757558 | 0.90 | APP (0.45) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL31757552 | 0.88 | LTA4H (0.40) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL31757537 | 0.87 | CHRNA7 (0.53) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL30375754 | 0.82 | CHRNB4 (0.48) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL30375430 | 0.82 | LTA4H (0.51) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL31757556 | 0.81 | CHRNB4 (0.47) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL30375153 | 0.80 | IMPDH2 (0.56) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL30375479 | 0.79 | LTA4H (0.49) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL30375571 | 0.78 | CYP17A1 (0.58) | APPLTA4HCHRNA7HDAC1CHRNB4 | |
| SCHEMBL3214637 | 0.78 | LTA4H (0.53) | APPLTA4HCHRNA7HDAC1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503436-B2 | Compounds and compositions for treating conditions associated with STING activity | NOVARTIS PHARMA AG (CH) | 2025-12-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503436-B2 | Compounds and compositions for treating conditions associated with STING activity | STING1, CGAS, IRF3 | APP 1734/4885LTA4H 1771/4885CHRNA7 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.