Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA2 | P00918 | 10/20 | 0.42 |
| ▸ | EEF2K | O00418 | 2/20 | 0.41 |
| ▸ | EEF2 | P13639 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487079 | 0.98 | MAPT (0.47) | MAPTCTDSP1CA1CA2EEF2K | |
| Dimethylamine SCHEMBL15348236 | 0.91 | MAPT (0.44) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL487095 | 0.83 | CA1 (0.51) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL487096 | 0.82 | CA1 (0.50) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL3312957 | 0.79 | CA1 (0.57) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL3458267 | 0.79 | CA1 (0.38) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL3312955 | 0.78 | CA1 (0.60) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL3313833 | 0.78 | KMT2A (0.63) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL3457800 | 0.78 | ACHE (0.41) | MAPTCTDSP1CA1CA2EEF2K | |
| Hydrochloric Acid SCHEMBL30980166 | 0.78 | CA1 (0.55) | MAPTCTDSP1CA1CA2EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006469-B2 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140031524-A1 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2014-01-30 | — | — | US | disclosed |
| US-8426618-B2 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120123109-A1 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2012-05-17 | — | — | US | disclosed |
| US-8093411-B2 | Cyanine dyes and their applications as luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2012-01-10 | — | — | US | disclosed |
| US-7910753-B2 | Cyanine dyes and their applications as luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2011-03-22 | — | — | US | disclosed |
| US-20100331543-A1 | Cyanine dyes and their applications as luminescence quenching compounds | DIWU ZHENJUN | 2010-12-30 | — | — | US | disclosed |
| US-20060223076-A1 | Cyanine dyes and their applications as luminescence quenching compounds | ANASPEC, INC. (US) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223076-A1 | Cyanine dyes and their applications as luminescence quenching compounds | TYR, ABCG2, CYBA | MAPT 1317/4885CTDSP1 4724/4885CA1 2730/4885 |
| US-20100331543-A1 | Cyanine dyes and their applications as luminescence quenching compounds | TYR, ABCG2, CYBA | MAPT 1317/4885CTDSP1 4724/4885CA1 2730/4885 |
| US-20120123109-A1 | Luminescence quenching compounds | ABCG2, TYR, GFPT1 | MAPT 1380/4885CTDSP1 4705/4885CA1 3176/4885 |
| US-20140031524-A1 | Luminescence quenching compounds | ABCG2, TYR, GFPT1 | MAPT 1380/4885CTDSP1 4705/4885CA1 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.