Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758596 | 0.92 | GPR119 (0.41) | GPR119ESR2USP30FPR3FPR2 | |
| SCHEMBL31415666 | 0.86 | MEN1 (0.46) | ESR2NR1H2NPC1RAB9AKDM1A | |
| SCHEMBL6959970 | 0.84 | KDM1A (0.52) | GPR119KDM1AHDAC1ALOX15TSHR | |
| SCHEMBL29993455 | 0.84 | KDM1A (0.52) | GPR119KDM1AHDAC1ALOX15TSHR | |
| SCHEMBL6970469 | 0.84 | KDM1A (0.52) | GPR119KDM1AHDAC1ALOX15TSHR | |
| SCHEMBL6968834 | 0.84 | KDM1A (0.52) | GPR119KDM1AHDAC1ALOX15TSHR | |
| SCHEMBL381500 | 0.84 | KDM1A (0.52) | GPR119KDM1AHDAC1ALOX15TSHR | |
| SCHEMBL17586453 | 0.81 | ESR2 (0.45) | GPR119ESR2USP30FPR3FPR2 | |
| SCHEMBL22471660 | 0.79 | ALK (0.41) | GPR119USP30FPR3FPR2KDM1A | |
| SCHEMBL15836945 | 0.78 | PDK2 (0.46) | GPR119ESR2USP30FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | GPR119 127/4885ESR2 3586/4885USP30 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.