SCHEMBL31758596

SCHEMBL31758596

CC(C)(C)OC(=O)N1CCC2(CC1)c1ccc(Br)cc1CC2O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.41
ESR2 Q92731 1/20 0.40
KDM1A O60341 3/20 0.40
USP30 Q70CQ3 2/20 0.40
FPR3 P25089 2/20 0.40
FPR2 P25090 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NR1H2 P55055 1/20 0.40
RORC P51449 3/20 0.39
BACE1 P56817 1/20 0.39
ALK Q9UM73 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
NAMPT P43490 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758554 0.92 GPR119 (0.41) GPR119ESR2KDM1AUSP30FPR3
SCHEMBL6968834 0.83 KDM1A (0.52) GPR119KDM1AALOX15TSHRNAMPT
SCHEMBL6970469 0.83 KDM1A (0.52) GPR119KDM1AALOX15TSHRNAMPT
SCHEMBL6959970 0.83 KDM1A (0.52) GPR119KDM1AALOX15TSHRNAMPT
SCHEMBL381500 0.83 KDM1A (0.52) GPR119KDM1AALOX15TSHRNAMPT
SCHEMBL29993455 0.83 KDM1A (0.52) GPR119KDM1AALOX15TSHRNAMPT
SCHEMBL25322292 0.81 ESR2 (0.44) GPR119ESR2KDM1AUSP30FPR3
SCHEMBL29475527 0.81 ESR2 (0.44) GPR119ESR2KDM1AUSP30FPR3
SCHEMBL31415666 0.81 MEN1 (0.46) ESR2KDM1ANPC1RAB9ANR1H2
SCHEMBL34461157 0.79 GPR119 (0.48) GPR119ESR2USP30FPR3FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 GPR119 127/4885ESR2 3586/4885KDM1A 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.