SCHEMBL3175871

SCHEMBL3175871

Cc1ccc(C23CC4CC(CC(C4)C2)C3)cc1Br

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
GAA P10253 2/20 0.51
POLB P06746 1/20 0.51
GFER P55789 1/20 0.51
LMNA P02545 3/20 0.47
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.41
EPHX2 P34913 3/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37
CNR2 P34972 2/20 0.36
RAD52 P43351 1/20 0.36
RAB9A P51151 1/20 0.36
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL27533340 0.95 KMT2A (0.47) MEN1KMT2AGAAPOLBGFER
SCHEMBL2706411 0.86 MEN1 (0.51) MEN1KMT2AGAAPOLBGFER
SCHEMBL31084981 0.86 MEN1 (0.51) MEN1KMT2AGAAPOLBGFER
SCHEMBL2763147 0.81 MEN1 (0.55) MEN1KMT2AGAAPOLBGFER
SCHEMBL3179225 0.79 MEN1 (0.43) MEN1KMT2AGAAPOLBGFER
SCHEMBL6449310 0.79 MEN1 (0.71) MEN1KMT2AGAAPOLBGFER
SCHEMBL22453632 0.79 ALDH1A1 (0.56) MEN1KMT2AGAAPOLBGFER
SCHEMBL34460060 0.79 ALDH1A1 (0.56) MEN1KMT2AGAAPOLBGFER
SCHEMBL792713 0.79 ALDH1A1 (0.56) MEN1KMT2AGAAPOLBGFER
SCHEMBL5808393 0.79 ALDH1A1 (0.56) MEN1KMT2AGAAPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed