Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20790078 | 0.93 | MEN1 (0.59) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL3975182 | 0.90 | MEN1 (0.57) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL559964 | 0.83 | MEN1 (1.00) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL2710580 | 0.81 | MEN1 (0.76) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL549446 | 0.80 | MEN1 (0.73) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL14829735 | 0.79 | MEN1 (0.71) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL2710154 | 0.79 | MEN1 (0.71) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL22453632 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL3175871 | 0.79 | MEN1 (0.51) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL14829050 | 0.79 | MEN1 (0.71) | MEN1KMT2AGAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195424-B2 | Antibiotic compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-14 | — | — | US | disclosed |
| US-20220095614-A1 | Antibiotic Compounds | THE GENERAL HOSPITAL CORPORATION | 2022-03-31 | — | — | US | disclosed |
| US-20220095614-A1 | Antibiotic Compounds | THE GENERAL HOSPITAL CORPORATION | 2022-03-31 | — | — | US | disclosed |
| US-11278025-B2 | Antibiotic compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2022-03-22 | — | — | US | disclosed |
| CN-110885320-B | Process for producing tertiary amine compound | 陕西莱特光电材料股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-20200190009-A1 | Antibiotic Compounds | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-06-18 | — | — | US | disclosed |
| US-20200190009-A1 | Antibiotic Compounds | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-06-18 | — | — | US | disclosed |
| CN-110240546-B | Preparation method of adamantyl-containing triphenylamine derivative | 陕西莱特光电材料股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-110885320-A | Process for producing tertiary amine compound | 陕西莱特光电材料股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| WO-2018213609-A1 | ANTIBIOTIC COMPOUNDS | AUSUBEL FREDERICK M (US) | 2018-11-22 | — | — | WO | disclosed |
| US-20050014767-A1 | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases | INCYTE CORPORATION | 2005-01-20 | — | — | US | disclosed |
| WO-2004066952-A2 | BENZOXAZOLE, BENZOTHIAZOLE, AND BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER AND OTHER DISEASES | INCYTE CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |
| US-20040097566-A1 | 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer | INCYTE SAN DIEGO INCORPORATED | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014767-A1 | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases | AR, CCNT1, BRD1 | MEN1 3126/4885KMT2A 1609/4885GAA 3018/4885 |
| US-20200190009-A1 | Antibiotic Compounds | CUTA, NRDC, CLPP | MEN1 4344/4885KMT2A 4368/4885GAA 1644/4885 |
| US-20220095614-A1 | Antibiotic Compounds | CUTA, NRDC, CLPP | MEN1 4344/4885KMT2A 4368/4885GAA 1644/4885 |
| US-12195424-B2 | Antibiotic compounds | CUTA, NRDC, CLPP | MEN1 4344/4885KMT2A 4368/4885GAA 1644/4885 |
| US-20040097566-A1 | 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer | PTPA, PTPRC, PTPRCAP | MEN1 3865/4885KMT2A 1090/4885GAA 1045/4885 |
| US-11278025-B2 | Antibiotic compounds | CUTA, NRDC, CLPP | MEN1 4344/4885KMT2A 4368/4885GAA 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.