Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176261 | 0.87 | KCNH2 (0.40) | CYP8B1 | |
| SCHEMBL4065072 | 0.81 | SIRT2 (0.39) | CYP8B1 | |
| SCHEMBL3175737 | 0.81 | CYP8B1 (0.40) | CYP8B1 | |
| SCHEMBL3178236 | 0.79 | KCNH2 (0.44) | — | |
| SCHEMBL4070188 | 0.78 | HTR1A (0.42) | — | |
| Hydrochloric Acid SCHEMBL3162918 | 0.78 | KCNH2 (0.44) | — | |
| SCHEMBL5752097 | 0.78 | KCNH2 (0.51) | — | |
| SCHEMBL3169008 | 0.78 | KCNH2 (0.40) | — | |
| SCHEMBL4067780 | 0.77 | CYP8B1 (0.38) | CYP8B1 | |
| SCHEMBL14434693 | 0.76 | SLC2A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |