Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065072 | 0.89 | SIRT2 (0.39) | CYP8B1 | |
| SCHEMBL3175737 | 0.88 | CYP8B1 (0.40) | KCNH2CYP8B1 | |
| SCHEMBL3176259 | 0.87 | CYP8B1 (0.39) | CYP8B1 | |
| SCHEMBL3178236 | 0.86 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4070188 | 0.85 | HTR1A (0.42) | — | |
| Hydrochloric Acid SCHEMBL3162918 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3169008 | 0.84 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL4225682 | 0.83 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL5752097 | 0.81 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4067780 | 0.78 | CYP8B1 (0.38) | KCNH2CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | claimed |
| EP-1773343-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-05-13 | — | — | EP | claimed |
| US-20070203127-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-08-30 | — | — | US | claimed |
| EP-1773343-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | claimed |
| WO-2006017326-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | claimed |
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |
| US-7648984-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |
| EP-1773343-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| US-20070203127-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-20070203127-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-20070203127-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| EP-1773343-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006017326-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203127-A1 | Antibacterial Agents | NQO2, NQO1, NDUFV2 | KCNH2 2586/4885CYP8B1 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.