Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 14/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 14/20 | 0.56 |
| ▸ | KCNJ5 | P48544 | 11/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184425 | 0.99 | KCNJ6 (0.57) | KCNJ6KCNJ3KCNJ5IRAK4MAPK14 | |
| SCHEMBL3185420 | 0.95 | KCNJ6 (0.56) | KCNJ6KCNJ3KCNJ5IRAK4 | |
| SCHEMBL2028299 | 0.81 | ORAI1 (0.47) | KCNJ6KCNJ3KCNJ5IRAK4MAPK14 | |
| SCHEMBL378881 | 0.80 | CDK8 (0.63) | MAPK14 | |
| SCHEMBL3388865 | 0.80 | MAPK14 (0.52) | KCNJ6KCNJ3KCNJ5MAPK14 | |
| SCHEMBL3165072 | 0.79 | CDK8 (0.45) | MAPK14 | |
| SCHEMBL2030579 | 0.79 | ORAI1 (0.47) | KCNJ6KCNJ3KCNJ5IRAK4 | |
| SCHEMBL3176499 | 0.78 | KCNJ6 (0.45) | KCNJ6KCNJ3KCNJ5IRAK4 | |
| SCHEMBL3185815 | 0.78 | KCNJ6 (0.57) | KCNJ6KCNJ3KCNJ5MAPK14 | |
| SCHEMBL14539234 | 0.78 | CDK8 (0.43) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-1970375-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2008-09-17 | — | — | EP | disclosed |
| EP-1970375-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | UROD, UTS2R, SLC14A1 | KCNJ6 3392/4885KCNJ3 3290/4885KCNJ5 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.