SCHEMBL3176700

SCHEMBL3176700

O=C(O)c1cc(Oc2cc(C(=O)O)c(C(=O)O)c(C(F)(F)F)c2)cc(C(F)(F)F)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ASPH Q12797 1/20 0.41
▸ TAS2R14 Q9NYV8 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ NOTUM Q6P988 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ USP2 O75604 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ CES2 O00748 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ TTR P02766 1/20 0.33
▸ PPOX P50336 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ NR1H2 P55055 1/20 0.33
▸ NR1H3 Q13133 1/20 0.33
▸ AKR1C3 P42330 1/20 0.33
▸ AKR1C2 P52895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29962893 0.95 POLB (0.42) ASPHTAS2R14ALDH1A1KDM4EHPGD
SCHEMBL9152486 0.95 POLB (0.42) ASPHTAS2R14ALDH1A1KDM4EHPGD
SCHEMBL29140668 0.92 POLB (0.43) TAS2R14ALDH1A1KDM4EHPGDPOLB
SCHEMBL29962299 0.91 AKR1C2 (0.40) ASPHPOLBTDP1AKR1C2
SCHEMBL9251468 0.91 AKR1C2 (0.40) ASPHPOLBTDP1AKR1C2
SCHEMBL29962860 0.88 MEN1 (0.43) KDM4EPOLBMEN1TTRPPOX
SCHEMBL9151921 0.88 MEN1 (0.43) KDM4EPOLBMEN1TTRPPOX
SCHEMBL29140655 0.85 MRGPRX4 (0.43) TAS2R14ALDH1A1KDM4EHPGD
SCHEMBL9156726 0.85 AKR1C2 (0.39) POLBTDP1AKR1C2
Ether SCHEMBL9156718 0.83 RXRA (0.39) ALDH1A1POLBAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 — — EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 — — US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 — — EP claimed
WO-2024071066-A1 METAL-CLAD LAMINATED PLATE 日鉄ケミカル&マテリアル株式会社 2024-04-04 — — WO disclosed
WO-2023189319-A1 AMINO COMPOUND, POLYAMIDE ACID AND POLYIMIDE USING SAID AMINO COMPOUND, AND METHOD FOR PRODUCING SAME 日鉄ケミカル&マテリアル株式会社 2023-10-05 — — WO disclosed
US-20210340325-A1 POLYIMIDE PRECURSOR, POLYIMIDE PRODUCED FROM SAME, AND FLEXIBLE DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-04 — — US disclosed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 — — US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 — — US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 — — EP disclosed
WO-2014192665-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICOH COMPANY, LTD. (JP) 2014-12-04 — — WO disclosed
US-20120177425-A1 GLOSSY SURFACE FORMING APPARATUS AND GLOSSY SURFACE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-07-12 — — US disclosed
EP-0616234-A2 Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-09-21 — — EP disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 — — US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 — — EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 — — US disclosed
US-5108201-A From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-28 — — US disclosed
EP-0454590-A2 Polyimide optical waveguide NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-30 — — EP disclosed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 — — EP disclosed
US-4735492-A POLYIMIDE-ISOIDOLOQUINAZOLINEDIONE HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-04-05 — — US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 — — EP disclosed
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