Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31773 | 0.84 | LOXL2 (0.52) | ALDH1A1HDAC6L3MBTL1MAPTTAS2R8 | |
| SCHEMBL30065107 | 0.81 | EPHX2 (0.47) | CYP2C9KMT2AHDAC6EPHX2DDB1 | |
| SCHEMBL9850086 | 0.80 | DDB1 (0.69) | CYP2D6CYP2C9KMT2AALDH1A1HDAC6 | |
| SCHEMBL1011633 | 0.80 | DDB1 (0.69) | CYP2D6CYP2C9KMT2AALDH1A1HDAC6 | |
| SCHEMBL9850110 | 0.78 | DDB1 (0.67) | CYP2D6CYP2C9KMT2AALDH1A1HDAC6 | |
| SCHEMBL5182904 | 0.78 | EPHX2 (0.47) | CYP2C9KMT2AEPHX2DDB1CRBN | |
| SCHEMBL3140629 | 0.77 | ENPP2 (0.46) | CYP2C9KMT2AALDH1A1HDAC6EPHX2 | |
| SCHEMBL1200393 | 0.75 | CYP2D6 (0.62) | CYP2D6CYP2C9HIF1AKMT2AFOLH1 | |
| SCHEMBL31572029 | 0.75 | CYP2D6 (0.62) | CYP2D6CYP2C9HIF1AKMT2AFOLH1 | |
| SCHEMBL670624 | 0.75 | CYP2C9 (0.55) | CYP2D6CYP2C9HIF1AKMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |