Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819205 | 1.00 | CAPN1 (0.54) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL3789459 | 1.00 | CAPN1 (0.54) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL12231157 | 0.90 | CAPN1 (0.52) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL7121471 | 0.88 | CAPN1 (0.55) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL7121470 | 0.88 | CAPN1 (0.55) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL3167032 | 0.87 | CAPN1 (0.56) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL3161411 | 0.87 | CAPN1 (0.56) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL30702652 | 0.87 | CAPN1 (0.56) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL17938810 | 0.87 | CAPN1 (0.56) | CAPN1APPMMP2MMP1MMP9 | |
| SCHEMBL3176677 | 0.87 | CAPN1 (0.56) | CAPN1APPMMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396083-A2 | PRODUCTS COMPRISING N-PHENYLPROPENOYL AMINO ACID AMIDES AND USES THEREOF | Nestec S.A. (CH) | 2011-12-21 | — | — | EP | claimed |
| WO-2010091981-A2 | PRODUCTS COMPRISING N-PHENYLPROPENOYL AMINO ACID AMIDES AND USES THEREOF | NESTEC S.A. (CH) | 2010-08-19 | — | — | WO | claimed |
| EP-2396083-A2 | PRODUCTS COMPRISING N-PHENYLPROPENOYL AMINO ACID AMIDES AND USES THEREOF | Nestec S.A. (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091981-A2 | PRODUCTS COMPRISING N-PHENYLPROPENOYL AMINO ACID AMIDES AND USES THEREOF | NESTEC S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |
| US-20100008976-A1 | Medical Use of N-Phenylpropenoyl-Amino Acid Derivatives and Related Compounds | Westfallsche Wilheims Universitat Munster (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008976-A1 | Medical Use of N-Phenylpropenoyl-Amino Acid Derivatives and Related Compounds | AADAT, DNPEP, DDC | CAPN1 2605/4885APP 804/4885MMP2 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.