SCHEMBL3176995

SCHEMBL3176995

O=C(C(=O)C(c1cccc2ccccc12)(c1cccc2ccccc12)c1cccc2ccccc12)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CNR2 P34972 3/20 0.43
ACP3 P15309 2/20 0.43
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
PTPRC P08575 1/20 0.39
KCNJ11 Q14654 2/20 0.38
ABCC9 O60706 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ8 Q15842 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
KIF11 P52732 1/20 0.38
HDAC1 Q13547 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
HDAC3 O15379 1/20 0.37
CYP2C9 P11712 1/20 0.37
HDAC8 Q9BY41 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27300466 0.79 ACP3 (0.49) KDM4EMEN1KMT2AACP3NR4A1
SCHEMBL30707929 0.74 KDM4E (0.49) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL8185296 0.74 KDM4E (0.49) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL28705859 0.73 KDM4E (0.47) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL29035967 0.73 KDM4E (0.47) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL8376253 0.72 HSD17B10 (0.47) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL8376250 0.72 KDM4E (0.46) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL1161290 0.72 KDM4E (0.53) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL29599325 0.72 KDM4E (0.53) KDM4EMEN1KMT2ACNR2ACP3
SCHEMBL29081148 0.71 KDM4E (0.50) KDM4EMEN1KMT2ACNR2ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100009383-A1 Method for the simple and rapid detection of cells and biomolecules by means of paramagnetic particles HOLGER KIESEWETTER (DE) 2010-01-14 US disclosed
EP-1766401-B8 METHOD FOR THE SIMPLE AND RAPID DETECTION OF CELLS AND BIOMOLECULES BY MEANS OF PARAMAGNETIC PARTICLES KIESEWETTER HOLGER (DE) 2009-07-08 EP disclosed
EP-1766401-B1 METHOD FOR THE SIMPLE AND RAPID DETECTION OF CELLS AND BIOMOLECULES BY MEANS OF PARAMAGNETIC PARTICLES KIESEWETTER HOLGER (DE) 2009-03-25 EP disclosed
US-7208281-B2 Ligands used for detecting prions KIESEWETTER HOLGER 2007-04-24 US disclosed
EP-1766401-A1 METHOD FOR THE SIMPLE AND RAPID DETECTION OF CELLS AND BIOMOLECULES BY MEANS OF PARAMAGNETIC PARTICLES Kiesewetter, Holger (DE) 2007-03-28 EP disclosed
EP-1360502-B1 LIGANDS USED FOR DETECTING PRIONS KIESEWETTER HOLGER (DE) 2006-02-01 EP disclosed
WO-2006005593-A1 METHOD FOR THE SIMPLE AND RAPID DETECTION OF CELLS AND BIOMOLECULES BY MEANS OF PARAMAGNETIC PARTICLES KIESEWETTER HOLGER (DE) 2006-01-19 WO disclosed
US-20040096902-A1 Ligands used for detecting prions KIESEWETTER HOLGER (DE) 2004-05-20 US disclosed
EP-1360502-A2 LIGANDS USED FOR DETECTING PRIONS Kiesewetter, Holger (DE) 2003-11-12 EP disclosed
WO-2002065133-A2 LIGANDS USED FOR DETECTING PRIONS KIESEWETTER HOLGER (DE) 2002-08-22 WO disclosed