Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707929 | 1.00 | KDM4E (0.49) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL16147542 | 0.84 | ACP3 (0.60) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL28705859 | 0.83 | KDM4E (0.47) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL29081148 | 0.81 | KDM4E (0.50) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL13199346 | 0.81 | CES1 (0.46) | ALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL3209247 | 0.80 | KDM4E (0.45) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL17289035 | 0.80 | KDM4E (0.44) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL22534073 | 0.79 | HSD17B10 (0.36) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL31515165 | 0.79 | HSD17B10 (0.36) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL4592642 | 0.78 | CYP2C9 (0.52) | KDM4EMEN1KMT2AACP3NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4340614-A1 | WEED CONTROL METHOD | Syngenta Crop Protection AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| WO-2022243155-A1 | WEED CONTROL METHOD | SYNGENTA CROP PROTECTION AG (CH) | 2022-11-24 | — | — | WO | disclosed |
| US-6034266-A | ANTIINFLAMMTORY AGENTS, ANALGESICS, ANTIARTHRITIC AGENTS | FUNDACAO OSWALDO CRUZ-FIOCRUZ (BR) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | SNCA, PARK7, PRNP | KDM4E 4800/4885MEN1 4376/4885KMT2A 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.