Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613484 | 0.76 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AACP3CNR2 | |
| SCHEMBL30707929 | 0.76 | KDM4E (0.49) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL8185296 | 0.76 | KDM4E (0.49) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL28705859 | 0.74 | KDM4E (0.47) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL8376250 | 0.74 | KDM4E (0.46) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL8376253 | 0.74 | HSD17B10 (0.47) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL1161290 | 0.73 | KDM4E (0.53) | KDM4EMEN1KMT2AACP3CNR2 | |
| SCHEMBL29599325 | 0.73 | KDM4E (0.53) | KDM4EMEN1KMT2AACP3CNR2 | |
| SCHEMBL3176995 | 0.73 | KDM4E (0.46) | KDM4EMEN1KMT2AACP3NR4A1 | |
| SCHEMBL29081148 | 0.73 | KDM4E (0.50) | KDM4EMEN1KMT2AACP3NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115231995-A | Mono-fluoro dibromo acetone derivative and preparation and application thereof | 上海应用技术大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115231995-A | Mono-fluoro dibromo acetone derivative and preparation and application thereof | 上海应用技术大学 | 2022-10-25 | — | — | CN | disclosed |