SCHEMBL3177258

SCHEMBL3177258

CC(C)c1cc(C(C)C)c(S[Bi](C)C)c(C(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
FABP4 P15090 3/20 0.41
FABP3 P05413 2/20 0.41
FABP5 Q01469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192221 0.84 GABRA1 (0.43) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL31502507 0.77 GABRA1 (0.48) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL915884 0.77 GABRA1 (0.48) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL3189037 0.76 GABRA1 (0.44) GABRA1GABRB2
SCHEMBL8884997 0.75 GABRA1 (0.46) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL17125433 0.73 GABRA1 (0.50) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL28111265 0.73 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL21415476 0.73 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8884992 0.73 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL6063410 0.73 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133357-B1 LIVING RADICAL POLYMERIZATION PROMOTER OTSUKA CHEMICAL CO LTD (JP) 2016-11-16 EP disclosed
US-8076430-B2 Living radical polymerization promoter OTSUKA CHEMICAL CO., LTD. (JP) 2011-12-13 US disclosed
US-20100022728-A1 LIVING RADICAL POLYMERIZATION PROMOTER OTSUKA CHEMICAL CO., LTD. (JP) 2010-01-28 US disclosed
EP-2133357-A1 LIVING RADICAL POLYMERIZATION PROMOTER Otsuka Chemical Holdings Co., Ltd. (JP) 2009-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022728-A1 LIVING RADICAL POLYMERIZATION PROMOTER DNMT1, CYP1B1, DNMT3B GABRA1 3794/4885GABRB2 2846/4885FABP4 4028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.