Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176227 | 0.86 | SMN1; SMN2 (0.37) | TSHRTDP1NPSR1MAPT | |
| SCHEMBL3176183 | 0.86 | TDP1 (0.36) | TSHRTDP1 | |
| SCHEMBL3160752 | 0.86 | ALDH1A1 (0.36) | TSHRTDP1MAPT | |
| SCHEMBL3168253 | 0.80 | MAPT (0.33) | TDP1CYP3A4MAPT | |
| SCHEMBL3171081 | 0.80 | TSHR (0.37) | TSHRTDP1PPARGNCOA2NCOA1 | |
| SCHEMBL3175025 | 0.74 | ALDH1A1 (0.40) | TSHRCYP3A4CYP2C9 | |
| SCHEMBL28559374 | 0.74 | TDP1 (0.53) | TSHRTDP1NPSR1CYP3A4MAPT | |
| SCHEMBL3177440 | 0.70 | TSHR (0.38) | TSHRTDP1PPARGNCOA2NCOA1 | |
| SCHEMBL31443221 | 0.70 | TDP1 (0.51) | TSHRTDP1NPSR1CYP3A4MAPT | |
| SCHEMBL125438 | 0.69 | TSHR (0.42) | TSHRTDP1PPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |