Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160752 | 0.88 | ALDH1A1 (0.36) | SMN1; SMN2TSHRTDP1ALDH1A1MAPT | |
| SCHEMBL3177434 | 0.86 | TSHR (0.38) | TSHRTDP1NPSR1MAPT | |
| SCHEMBL3176183 | 0.86 | TDP1 (0.36) | SMN1; SMN2TSHRTDP1 | |
| SCHEMBL3168253 | 0.82 | MAPT (0.33) | TDP1MAPT | |
| SCHEMBL3178795 | 0.79 | GAA (0.42) | SMN1; SMN2TSHRGAAMGAMSI | |
| SCHEMBL3177400 | 0.78 | GAA (0.39) | SMN1; SMN2TSHRGAAMGAMSI | |
| SCHEMBL3167771 | 0.73 | PPID (0.48) | SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8939889 | 0.70 | GAA (0.65) | SMN1; SMN2TSHRGAAMGAMSI | |
| SCHEMBL19105432 | 0.68 | TSHR (0.43) | SMN1; SMN2TSHRGAAMGAMSI | |
| SCHEMBL8824241 | 0.68 | TSHR (0.50) | SMN1; SMN2TSHRGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |