Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178665 | 0.92 | PTGER1 (0.64) | PTGER1P2RY14LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3180804 | 0.92 | PTGER1 (0.71) | PTGER1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL13532614 | 0.91 | PTGER1 (0.59) | PTGER1TP53LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3169961 | 0.90 | PTGER1 (0.60) | PTGER1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL17804025 | 0.90 | PTGER1 (0.58) | PTGER1TP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3178649 | 0.89 | PTGER1 (0.57) | PTGER1TP53LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3186310 | 0.89 | PTGER1 (0.63) | PTGER1TP53LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3186918 | 0.88 | PTGER1 (0.57) | PTGER1TP53MAP3K5 | |
| Hydrochloric Acid SCHEMBL3188205 | 0.88 | PTGER1 (0.63) | PTGER1LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL3178984 | 0.87 | PTGER1 (0.56) | PTGER1P2RY14MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022486-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-01-28 | — | — | US | claimed |
| US-20100022486-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-01-28 | — | — | US | disclosed |
| US-20100022486-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-01-28 | — | — | US | disclosed |
| US-20100022486-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-01-28 | — | — | US | disclosed |
| WO-2008074832-A2 | ISOQUINOLINECARBOXAMIDES AS INHIBITORS OF STEAROYL-COA DESATURASE ( SCD) | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022486-A1 | COMPOUNDS | SCD, CYP11B2, SCD5 | PTGER1 681/4885TP53 4743/4885HTR2C 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.