SCHEMBL317779

SCHEMBL317779

COC(=O)C1CCC(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.46
KMT2A Q03164 2/20 0.45
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
CNR1 P21554 1/20 0.41
DAGLA Q9Y4D2 1/20 0.41
TSHR P16473 1/20 0.39
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78947 1.00 LMNA (0.48) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL475421 1.00 LMNA (0.48) LMNAGAAKMT2APOLBSMN1; SMN2
Methylene Chloride SCHEMBL28127319 0.93 LMNA (0.47) LMNAGAAKMT2APOLBSMN1; SMN2
Methylene Chloride SCHEMBL28127317 0.93 LMNA (0.47) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL4939720 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL4939718 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL5026447 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL2790715 0.87 LMNA (0.43) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL30948745 0.87 LMNA (0.45) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL6810038 0.87 KMT2A (0.41) LMNAGAAKMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129094-A1 NEW QUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-24 US claimed
WO-2025073270-A1 BIPHENYL TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 海南因瑞生物医药科技有限公司 2025-04-10 WO claimed
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
CN-117957223-A Quinoline derivatives 礼蓝动物保健有限公司 2024-04-30 CN claimed
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-114763356-B Pyrrolo-benzodiazepine compound, and preparation method and application thereof 沈阳药科大学 2023-06-20 CN claimed
WO-2023036821-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2023-03-16 WO claimed
EP-4148052-A1 NEW QUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2023-03-15 EP claimed
CN-114763356-A Pyrrolobenzodiazepine compounds, and preparation method and application thereof 沈阳药科大学 2022-07-19 CN claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0594608-A4 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1993-03-15 EP claimed
US-5137714-A Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid UNILEVER PATENT HOLDINGS B.V. (NL) 1992-08-11 US claimed
WO-1991014672-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-03 WO claimed
US-4912232-A Preparation of N-hydrocarbylcarbonyl-5-(1-hydrocarbylcarbonyloxy)hydrocarbyl-pyrrolidin-2-one DOW CHEMICAL COMPANY (US) 1990-03-27 US claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129094-A1 NEW QUINOLINE DERIVATIVES RECQL, QTRT2, NQO2 LMNA 1309/4885GAA 1046/4885KMT2A 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.