SCHEMBL78947

SCHEMBL78947

COC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.46
KMT2A Q03164 2/20 0.45
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
CNR1 P21554 1/20 0.41
DAGLA Q9Y4D2 1/20 0.41
TSHR P16473 1/20 0.39
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36
BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317779 1.00 LMNA (0.48) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL475421 1.00 LMNA (0.48) LMNAGAAKMT2APOLBSMN1; SMN2
Methylene Chloride SCHEMBL28127319 0.93 LMNA (0.47) LMNAGAAKMT2APOLBSMN1; SMN2
Methylene Chloride SCHEMBL28127317 0.93 LMNA (0.47) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL4939720 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL4939718 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL5026447 0.89 KMT2A (0.42) LMNAGAAKMT2APOLBCNR1
SCHEMBL2790715 0.87 LMNA (0.43) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL30948745 0.87 LMNA (0.45) LMNAGAAKMT2APOLBSMN1; SMN2
SCHEMBL6810038 0.87 KMT2A (0.41) LMNAGAAKMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025099154-A1 OILY BIOCIDE COMPOSITIONS COMPRISING DIAMINE COMPOUNDS EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2025-05-15 WO claimed
WO-2025099168-A1 STORABLE MULTI-COMPONENT COMPOSITIONS COMPRISING A STABLE BIOCIDE COMPONENT EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2025-05-15 WO claimed
WO-2025073270-A1 BIPHENYL TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 海南因瑞生物医药科技有限公司 2025-04-10 WO claimed
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
CN-114763356-B Pyrrolo-benzodiazepine compound, and preparation method and application thereof 沈阳药科大学 2023-06-20 CN claimed
CN-114395858-A Preparation method of hydrophobic tough non-woven fabric 扬州丽铂环保材料有限公司 2022-04-26 CN claimed
CN-211158684-U Extraction device for preparing L-pyroglutamic acid methyl ester 四川同晟氨基酸有限公司 2020-08-04 CN claimed
CN-110628740-A Preparation method and application of peptidomimetics small molecular compound simulating DOT1L polypeptide 中国药科大学 2019-12-31 CN claimed
CN-107383025-B The preparation method of endocyclic compound 吉林凯莱英医药化学有限公司 2019-04-26 CN claimed
CN-105294700-B A kind of preparation method of 2- oxo -3,8- diazabicylo [3.2.1] octane -8- carboxylic acid tert-butyl ester 上海合全药业股份有限公司 2019-01-08 CN claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342055-B1 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1994-01-12 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0594608-A4 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1993-03-15 EP claimed
US-5137714-A Anhydrous cosmetic composition comprising stable lower alkyl esters of pyroglutamic acid UNILEVER PATENT HOLDINGS B.V. (NL) 1992-08-11 US claimed
WO-1991014672-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-03 WO claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed