Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167771 | 0.90 | PPID (0.48) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL3178279 | 0.88 | TSHR (0.48) | HTTL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3175252 | 0.87 | ALDH1A1 (0.44) | HTTL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3175025 | 0.87 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KDM4EGAAMAPK1 | |
| SCHEMBL3161568 | 0.76 | CYP1A2 (0.43) | HTTL3MBTL1ALDH1A1KDM4EABCB1 | |
| SCHEMBL10382174 | 0.76 | HTT (0.45) | HTTL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL14046783 | 0.73 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL31174375 | 0.73 | ALDH1A1 (0.58) | HTTL3MBTL1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL3692691 | 0.73 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL18510019 | 0.73 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |