Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177913 | 0.90 | HTT (0.47) | ALDH1A1NPSR1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL3175025 | 0.88 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPK1KDM4ECYP1A2 | |
| SCHEMBL3178279 | 0.86 | TSHR (0.48) | ALDH1A1L3MBTL1MAPK1CYP3A4CYP2C9 | |
| SCHEMBL3175252 | 0.85 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL1912567 | 0.81 | PPID (0.52) | PPIDLTA4HPKMALDH1A1L3MBTL1 | |
| SCHEMBL3194496 | 0.79 | PPID (0.50) | PPIDLTA4HPKMALDH1A1L3MBTL1 | |
| SCHEMBL3168675 | 0.79 | PPID (0.50) | PPIDLTA4HPKMNPSR1SMN1; SMN2 | |
| SCHEMBL21959514 | 0.79 | PPID (0.50) | PPIDLTA4HPKMALDH1A1L3MBTL1 | |
| SCHEMBL21959513 | 0.79 | PPID (0.50) | PPIDLTA4HPKMALDH1A1L3MBTL1 | |
| SCHEMBL6518216 | 0.76 | PPID (0.59) | PPIDLTA4HPKMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |