⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435528 | 0.97 | — | — | |
| SCHEMBL17639 | 0.97 | — | — | |
| SCHEMBL27768617 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL8812851 | 0.95 | — | — | |
| Bromide SCHEMBL29506576 | 0.93 | NOS2 (0.91) | — | |
| SCHEMBL6859312 | 0.89 | NOS2 (0.83) | — | |
| SCHEMBL1181839 | 0.89 | NOS2 (0.83) | — | |
| Alcohol SCHEMBL28917587 | 0.87 | NOS2 (0.79) | — | |
| Ammonia Solution, Strong SCHEMBL3174065 | 0.87 | NOS2 (0.79) | — | |
| Ammonia Solution, Strong SCHEMBL3170954 | 0.83 | NOS2 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7651979-B2 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-01-26 | — | — | US | disclosed |
| US-20050227290-A1 | Novel coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | disclosed |
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |