⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640452 | 0.85 | LMNA (0.38) | — | |
| SCHEMBL4992703 | 0.78 | LMNA (0.40) | — | |
| SCHEMBL7806387 | 0.77 | — | — | |
| SCHEMBL32691462 | 0.74 | — | — | |
| SCHEMBL1831345 | 0.74 | — | — | |
| SCHEMBL4998321 | 0.74 | FDPS (0.40) | — | |
| SCHEMBL1553705 | 0.73 | — | — | |
| SCHEMBL1449044 | 0.73 | — | — | |
| SCHEMBL11466197 | 0.73 | — | — | |
| Carbromal SCHEMBL4351621 | 0.72 | CRBN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770514-B2 | Tamper-resistant pharmaceutical dosage forms | ExxPharma Therapeutics LLC (US) | 2017-09-26 | — | — | US | claimed |
| US-20150064250-A1 | Tamper-Resistant Pharmaceutical Dosage Forms | ExxPharma Therapeutics LLC (US) | 2015-03-05 | — | — | US | claimed |
| US-7214381-B2 | Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels | ANTARES PHARMA IPL AG (CH) | 2007-05-08 | — | — | US | claimed |
| US-20030199426-A1 | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels | ANTARES PHARMA, INC. | 2003-10-23 | — | — | US | claimed |
| CN-1122024-C | Process for converting hydroxy heteroaromatic compounds to arylamines | AVENTIS PHARMA INC (US) | 2003-09-24 | — | — | CN | claimed |
| EP-1323431-A2 | Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels | Antares Pharma IPL AG (CH) | 2003-07-02 | — | — | EP | claimed |
| EP-1307232-A1 | NOVEL COMPOSITION FOR TRANSDERMAL AND/OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE COMPOUNDS THAT ENSURES ADEQUATE THERAPEUTIC LEVELS | Antares Pharma IPL AG (CH) | 2003-05-07 | — | — | EP | claimed |
| WO-2002006826-B1 | SINGLE-PATIENT DRUG TRIALS USED WITH ACCUMULATED DATABASE | OPT E SCRIP INC (US) | 2002-04-04 | — | — | WO | claimed |
| US-20020032581-A1 | Single-patient drug trials used with accumulated database: risk of habituation | OPT-E-SCRIP, INC. | 2002-03-14 | — | — | US | claimed |
| WO-2002011768-A1 | NOVEL COMPOSITION FOR TRANSDERMAL AND/OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE COMPOUNDS THAT ENSURES ADEQUATE THERAPEUTIC LEVELS | ANTARES PHARMA IPL AG (CH) | 2002-02-14 | — | — | WO | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| US-6034241-A | Process for converting hydroxy heteroaromatics to arylamines | HOECHST MARION ROUSSEL INC. (US) | 2000-03-07 | — | — | US | claimed |
| CN-1238763-A | Process for converting hydroxy heteroaromatics to arylamines | HOECHST MARION ROUSSEL INC (US) | 1999-12-15 | — | — | CN | claimed |
| EP-0944600-A1 | PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES | HOECHST MARION ROUSSEL, INC. (US) | 1999-09-29 | — | — | EP | claimed |
| CN-1222915-A | Alkylation and Schmeis rearrangement of hydroxyaromatic compounds | HOECHST MARION ROUSSEL INC (US) | 1999-07-14 | — | — | CN | claimed |
| EP-0888380-A1 | PROCESS FOR ALKYLATING AND SMILES REARRANGEMENT OF HYDROXY AROMATICS | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-07 | — | — | EP | claimed |
| US-5817874-A | Process for alkylating and smiles rearrangement of hydroxy aromatics | HOECHST MARION ROUSSEL, INC. (US) | 1998-10-06 | — | — | US | claimed |
| WO-1998023589-A1 | PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-04 | — | — | WO | claimed |
| WO-1997034916-A1 | PROCESS FOR ALKYLATING AND SMILES REARRANGEMENT OF HYDROXY AROMATICS | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-25 | — | — | WO | claimed |
| US-4805340-A | Humane glue trap for rats, mice and other vermin having carbomal in the bait | TAMBY CHEMICAL CORP. (US) | 1989-02-21 | — | — | US | claimed |